Clinical stages of Fuch’s dystrophy.

Stage: 1

Asymptomatic

Central cornel guttae

Pigments on posterior corneal surface

Gray and thickened appearance of Descemet’s membrane

In advanced cases, endothelium has a ‘beaten-bronze’( melanin deposition).

Stage: 2

Painless decrease in vision and glare, severe on awakening

Stromal edema (ground glass appearance)

Microcystic epithelial edema (occurs when stromal thickness has been increased by about 30%).

Stage: 3

Episodes of pain

Formation of epithelial and sub epithelial bullae, which rupture.

Stage: 4

Visual acuity reduced to hand movements

No painful attacks

Appearance of sub epithelial scar tissue.

 

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